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Legend：
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Phase Ⅲ
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Phase II
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Phase I
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IND Enabling
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PCC
TBD=Target to be disclosed.
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Therapeutic AreaCandidateTargetIndicationMolecular FormClinical Phase
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Endocrinology & Metabolism
Endocrinology & Metabolism-
CandidateTargetIndicationMolecular FormClinical Phase
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GenSci155
IGF-1RAIS, BPD, sPIGHDPeptide Conjugate (QW)Phase I -
GenSci134GHR (Monthly)AGHD, PGHD, ISSFusion Protein (QM)Phase I
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GenSci164PTH (Weekly)PTHPeptide Conjugate (QW)IND Enabling
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GenSciP133PTH*RANKLOsteoporosisBi-function?ProteinIND Enabling
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Women’s Health
Women’s Health
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci074NK3RVMSSMPhase Ⅲ
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GenSci142
GardnerellaBVLysinPhase I
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GenSci161
IL1β*IL1αEMBsAbPhase I
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Rheumatology
Rheumatology
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci120PD1-high T-cell depleterRAmAbPhase II
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Dermatology
Dermatology
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci161
IL1β*IL1αHSBsAbPhase I
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Renal
Renal
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci144SLC6A19CKD, PKUSMIND Enabling
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CNS
CNS
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci136APRIL*BAFFgMGFusion ProteinPhase I
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GenSci155
IGF-1RAISPeptide Conjugate (QW)IND Enabling
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GenSciP165
TfR-APP siRNAAlzheimer's DiseaseAntibody Oligonucleotide Conjugate (AOC)PCC
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Respiratory
Respiratory
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci124
CFTRCFmRNA (inhaler)IND Enabling
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GenSci117
MMP7IPFsiRNA (inhaler)IND Enabling
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GenSci111
CTGFIPFsiRNA (inhaler)IND Enabling
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GenSci118
RAGECOPDsiRNA (inhaler)PCC
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GS24-B044
MUC5ACCOPD, BEsiRNA (inhaler)PCC
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Ophthalmology
Ophthalmology
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci136APRIL*BAFFOMGFusion ProteinPhase I
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GenSci098TSHRTED, GDmAbPhase I
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GenSci161
IL1β*IL1αNIUBsAbPhase I
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GenSci148VEGF A/C/D *Ang2wAMDFusion ProteinIND Enabling
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GenSciP181TBDdAMDsiRNAPCC
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Oncology
Oncology
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CandidateTargetIndicationMolecular FormClinical Phase
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GenSci145PI3KαBCSMPhase I
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GenSci143
PSMA*B7H3PCaBsAb Topo1i ADCPhase I
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GenSci139
EGFR*HER2UCBsAb Topo1i ADCPhase I
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GenSci140
FRα*FRαOCBiparatopic Topo1i ADCPhase I
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GenSci128TP53 Y220CSolid TumorSMPhase I
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GenSciP153PSMAmCRPCAc-225 RLTIND Enabling
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GenSci180
CDH17*CEACRCBsAb Topo1i ADCIND Enabling
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Endocrinology & Metabolism-
GenSci155
AIS, BPD, sPIGHD
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GenSci134
AGHD, PGHD, ISS
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GenSci164
PTH
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GenSciP133
Osteoporosis
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Women’s Health-
GenSci074
VMS
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GenSci142
BV
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GenSci161
EM
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Rheumatology-
GenSci120
RA
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Dermatology-
GenSci161
HS
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Renal-
GenSci144
CKD, PKU
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CNS-
GenSci136
gMG
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GenSci155
AIS
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GenSciP165
Alzheimer's Disease
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Respiratory-
GenSci124
CF
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GenSci117
IPF
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GenSci111
IPF
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GenSci118
COPD
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GS24-B044
COPD, BE
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Ophthalmology-
GenSci136
OMG
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GenSci098
TED, GD
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GenSci161
NIU
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GenSci148
wAMD
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GenSciP181
dAMD
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Oncology-
GenSci145
BC
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GenSci143
PCa
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GenSci139
UC
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GenSci140
OC
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GenSci128
Solid Tumor
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GenSciP153
mCRPC
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GenSci180
CRC
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